
Mr. Hyde as portrayed by Fredric March in Rouben Mamoulian's 1931 film "Dr. Jekyll and Mr. Hyde" makeup by Wally Westmore.
"Dr. Jekyll and Mr. Hyde" featured groundbreaking effects for its day, scenes were filmed using a red filter with March already wearing makeup, but because of the filter the makeup was invisible. When the circular filter was gradually rotated from red to blue, audiences saw March change from Dr. Jekyll to Mr. Hyde, right before their eyes and seemingly without camera tricks.
Fredric March won the Academy Award for Best Actor.